J Korean Pediatr Soc.  1980 Sep;23(9):687-694.

Hemagglutination and Drug Resistance of Escherichia coli Isolated from Children

• Park SB
• Rhim ST
• Kim KC
• Ha TY

Abstract

A hemagglutination(HA)-typing system has been developed for the presumptive identification of enterotoxigenic Escherichia coli(ETEC) possessing the colonization factor antigens(CFA) Seventy-seven E. coli strains from pediatric patients with or without diarrhea were examined for the mannose-resistant(MR) HA or mannose-sensitive(MS) HA of human, bovine, chicken, and guinea pig erythrocytes and their antibiotic resestances. A significant proportion(68%) of the isolates exhibited the HA pattern of NNNN(experssed in the order human/bovin/chicken/guinea pig erythrocytes), and 10% of the isolates exhibited NNSS, known as the pattern about half of enteropathogenic E. coli serogroups produced. Sixty-nine strains(88%) were resistant to one or more antibiotics; 55(80%) were reristant to four or more antibiotics. The strains showed multiple drug resistance were more higher in HA-positive strains(92% of HA-positive strains) than in HA-negative strains(76% of HA-negative strains) and all of the HA-positive strains with human erythrocytes were resistant to 4 or more antibiotics. There were no significant differences between HA patterns and antibiotic resistance in both the strains from the patients with or without diarrhea. In summary, although the causative organisms in cases of diarrhea of this study have not been established, the date herein suggested that ETEC possessing CFA which produce RRRN or NRRN HA pattern was not participated in this diarrhea.

MeSH Terms

Animals
Anti-Bacterial Agents
Chickens
Child*
Colon
Diarrhea
Drug Resistance*
Drug Resistance, Microbial
Drug Resistance, Multiple
Enteropathogenic Escherichia coli
Enterotoxigenic Escherichia coli
Erythrocytes
Escherichia coli*
Escherichia*
Guinea Pigs
Hemagglutination*
Humans
Anti-Bacterial Agents