J Korean Radiol Soc.
1997 Jun;36(6):1059-1064.
CT and MR Findings in Retinoblastoma: Correlation with Histopathologic Examination
- Affiliations
-
- 1Department of Radiology, Seoul National University College of Medicine.
- 2Department of Pathology, Seoul National University College of Medicine.
- 3Department of Ophthalmology, Seoul National University College of Medicine.
Abstract
- PURPOSE
To evaluate histopathologic correlation of the component of the lesion on CT and MR of retinoblastomas.
MATERIALS AND METHODS
Gross pathologic findings of 24 enucleated eyeballs in 24 patients with retinoblastomas were compared with preoperative CT (n=19) and MR (n=5) findings. In eight eyeballs, in which there were findings other than mass, histopathologic findings were reviewed and correlated with image findings.
RESULTS
Retinal detachment and subretinal hemorrhage which were not detected on CT were demonstrated in two of eight eyeballs on histopathologic examination. In one eyeball, retinal detachment and subretinal effusion were detected on both CT and in a pathologic specimen. In two eyeballs with peripheral heterogeneous MR enhancement of the masses, tumor necrosis and calcification were demonstrated in the central non-enhancing portion of the mass. In two eyeballs, linear soft tissue along the retina apart from the main mass were revealed as tumor spread along the retinal surface. In one patient, retinal thickening on MR was presumed to be an MR artifact and no lesion was found in the gross specimen.
CONCLUSION
On CT, retinal detachment and subretinal hemorrhage associated with retinoblastoma can mimic mass, and tumor spread along the retinal surface can be seen as a linear retinal lesion. On MR, tumor necrosis and calcification can be a cause of heterogeneous enhancement.
