J Korean Soc Coloproctol.  2011 Dec;27(6):282-286. 10.3393/jksc.2011.27.6.282.

Clinical Characteristics of Ischemic Colitis According to Location

• Chang HJ
• Chung CW
• Ko KH
• Kim JW

• KMID: 2101575
• DOI: http://doi.org/10.3393/jksc.2011.27.6.282

Abstract

PURPOSE
The aim of this study was to analyze various clinical characteristics of ischemic colitis according to its location.
METHODS
The medical records of 92 cases of gastrointestinal ischemic colitis (IC) diagnosed at Bundang CHA Hospital from 1995 to 2008 were reviewed and analyzed retrospectively. The patients were diagnosed by using colonoscopic biopsies or laparotomy findings. The patients were divided into two groups, right and left, according to the main involvement area of the IC at the embryologic boundary line of the distal transverse colon, and the two groups were compared as to clinical characteristics and co-morbid diseases.
RESULTS
Left IC was present in 59 patients (64.1%) and right IC in 33 patients (35.9%). No differences between the two groups in terms of clinical characteristics, cardiovascular disease and diabetes mellitus were observed. However, in 16 cases with renal failure, 10 patient had right IC and 6 patients had left IC, and this difference had statistical significance (P = 0.014). Among the 16, the 11 patients requiring hemodialysis included 8 with right IC (24.2%) and 3 with left IC (5.1%; P = 0.009). Among the 19 cases of severe IC requiring surgical treatment or involving mortality, irrespective of surgery, 11 patients showed right IC and 8 patients showed left IC (P = 0.024).
CONCLUSION
Right-side ischemic colitis was significantly associated with renal failure and disease severity, so patients with right-side colon ischemia should be more carefully observed and managed.

Keyword

Colitis, Ischemic; Localization; Severity

MeSH Terms

Biopsy
Cardiovascular Diseases
Colitis, Ischemic
Colon
Colon, Transverse
Diabetes Mellitus
Humans
Ischemia
Laparotomy
Medical Records
Renal Dialysis
Renal Insufficiency
Retrospective Studies