Korean J Otorhinolaryngol-Head Neck Surg.  2015 Oct;58(10):710-712. 10.3342/kjorl-hns.2015.58.10.710.

A Case of Milk-Alkali Syndrome in a Patient with Hypoparathyroidism after Total Thyroidectomy

• Joo BY
• Park HS
• Hong JC

• KMID: 2100498
• DOI: http://doi.org/10.3342/kjorl-hns.2015.58.10.710

Abstract

Milk-alkali syndrome (MAS) is a disorder featuring hypercalcemia, renal failure and metabolic alkalosis due to ingestion of large amounts of calcium and absorbable alkali. MAS was first reported after Milk-alkali treatment of peptic ulcer in early 1910. But since the late 20th century, the wide availability and increasing consumption of calcium carbonate and vitamin D supplementation mostly for osteoporosis prevention has been noted as reemerging clinical backgrounds of MAS. We experienced a case of a woman who had taken calcium and vitamin D for a year due to hypoparathyroidism after total thyroidectomy. She was admitted suffering from nausea, vomiting, anorexia and irritability with the triad of hypercalcemia, metabolic alkalosis and acute renal insufficiency. Every abnormal symptom, calcium level and renal function were normalized with fluid and diuretic therapies.

Keyword

Alkalosis; Calcium; Hypercalcemia; Renal failure

MeSH Terms

Acute Kidney Injury
Alkalies
Alkalosis
Anorexia
Calcium
Calcium Carbonate
Eating
Female
Humans
Hypercalcemia*
Hypoparathyroidism*
Nausea
Osteoporosis
Peptic Ulcer
Renal Insufficiency
Thyroidectomy*
Vitamin D
Vomiting
Alkalies
Calcium
Calcium Carbonate
Vitamin D