J Korean Soc Med Inform.  2002 Mar;8(1):63-70.

A Quantitative Analysis for Pre-processing Algorithm of Aberration Chromosome Observation

• Jeon GR
• Chang YH
• Eom SH

Abstract

The task of chromosome analysis is the classification of human chromosomes. The feature parameter of chromosome is very important information for chromosome analysis. The special preprocessing algorithm is required to extracting them. In this paper, we performed quantitative analysis for preprocessing algorithm of observation of chromosomal aberrations. Two algorithms is used MAT and reconstruction. The morphological feature parameters were centromeric index(C.I.), relative length ratio(R.L.), relative area ratio(R.A.) and chromosome length(C.L.), and the density and width profiles. The reconstruction of chromosome images by this reconstruction algorithm was appeared as effective algorithms to observe and extract chromosome parameter.

Keyword

Chromosome; Preprocessing Algorithm; Feature Parameter

MeSH Terms

Chromosome Aberrations
Chromosomes, Human
Classification
Humans