J Korean Soc Radiol.  2012 Aug;67(2):117-120. 10.3348/jksr.2012.67.2.117.

CT Findings of Primary Localized Amyloidosis of the Urinary Bladder: A Case Report

Affiliations
  • 1Department of Radiology, Keimyung University College of Medicine, Dongsan Hospital, Daegu, Korea. kseehdr@dsmc.or.kr
  • 2Department of Pathology, Keimyung University College of Medicine, Dongsan Hospital, Daegu, Korea.

Abstract

Primary localized amyloidosis is a rare disease that impairs the organs and tissue function, caused by extracellular deposition of amyloid protein. Although amyloid proteins can be deposited in localized or systemic organs, the bladder is a rare site. CT showed diffuse infiltrative mass in the left urinary bladder wall, and the left ureterovesical junction with enhancement and perivesical invasion, which mimics urothelial carcinoma. However, pathological diagnosis was localized primary amyloidosis. We report here on the CT findings of a rare case of primary localized amyloidosis of the urinary bladder with brief review of the literature.


MeSH Terms

Amyloid
Amyloidogenic Proteins
Amyloidosis
Rare Diseases
Urinary Bladder
Amyloid
Amyloidogenic Proteins
Amyloidosis

Reference

1. Wilkinson M, Fanning DM, Flood H. Primary bladder amyloidosis. BMJ Case Rep. 2011. 2011.
2. Kawashima A, Alleman WG, Takahashi N, Kim B, King BF Jr, LeRoy AJ. Imaging evaluation of amyloidosis of the urinary tract and retroperitoneum. Radiographics. 2011. 31:1569–1582.
3. Ng CS, Wan S, Yim AP, Vale J. Idiopathic localised bladder amyloidosis: rare cause of haematuria. Int Urol Nephrol. 2002. 34:55–58.
4. Merlini G, Westermark P. The systemic amyloidoses: clearer understanding of the molecular mechanisms offers hope for more effective therapies. J Intern Med. 2004. 255:159–178.
5. Urban BA, Fishman EK, Goldman SM, Scott WW Jr, Jones B, Humphrey RL, et al. CT evaluation of amyloidosis: spectrum of disease. Radiographics. 1993. 13:1295–1308.
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