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J Korean Soc Radiol.  2010 Nov;63(5):463-469. 10.3348/jksr.2010.63.5.463.

Islet Cell Tumors of the Pancreas: A Variety of MultiphaseDynamic Imaging Findings with Pathologic Correlations Focusing on Nonfunctioning Tumors and Insulinomas

Affiliations
  • 1Department of Diagnostic Radiology, Gangnam Severance Hospital,Yonsei University College of Medicine, Korea. yjsrad97@yuhs.ac
  • 2Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Korea.

Abstract

Islet cell tumors (ICTs) are rare pancreatic neoplasms of neuroendocrine origin, posing a diagnostic challenge to radiologists. We illustrated a spectrum of features of pancreatic ICTs that could be found on multiphase dynamic CT or MRI, and elucidated the histopathologic characteristics by determining the contrast enhancement pattern of the lesions. Various enhancement patterns were dependant on the internal composition of the tumor, that is, the proportion of vascular densities for early enhancement and non-hypervascular interstitial tissue for late enhancement regardless of the size or functional behavior. This knowledge of the imaging-pathologic spectrum of ICTs could be helpful for the proper differential diagnosis from other pancreatic tumors.


MeSH Terms

Adenoma, Islet Cell
Diagnosis, Differential
Insulinoma
Islets of Langerhans
Pancreatic Neoplasms
Tomography, X-Ray Computed
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