J Korean Surg Soc.  2002 Sep;63(3):252-255.

Primary Plasmacytoma of the Thyroid

• Koh YS
• Gaegal YJ
• Yoon JH
• Park JW
• Nam JH
• Lee MC

Abstract

Primary plasmacytoma of the thyroid gland is a rare disease which is known to comprise only about 0.3% of all thyroid malignancies, resulting in its clinicopathologic features remaining incompletely understood. Clinical manifestations of plasmacytoma of the thyroid, such as painless, non-tender, and non-toxic goitrous enlargement, are similar to those of other thyroid malignancies. Plasmacytoma of the thyroid can be diagnosed finally after ruling out all the other systemic diseases. Here, we report a case of a 49-year-old female patient with primary plasmacytoma of the thyroid, who had been suffering from anterior neck swelling in the thyroid region for 10 months. She had undergone total thyroidectomy under the diagnosis of an adenomatous goiter. However, pathologic report revealed plasmacytoma of the thyroid associated with Hashimoto thyroiditis. Intracytoplasmic monoclonal immunoglobulin (IgG) was demonstrated in tissue sections. Postoperative roentgenographic skeletal survey and bone marrow examination results were normal. We present a case of primary plasmacytoma of the thyroid along with a brief review of the literature.

Keyword

Plasmacytoma; Thyroid; Hashimoto's thyroiditis

MeSH Terms

Bone Marrow Examination
Diagnosis
Female
Goiter
Hashimoto Disease
Humans
Immunoglobulins
Middle Aged
Neck
Plasmacytoma*
Rare Diseases
Thyroid Gland*
Thyroidectomy
Immunoglobulins