Korean Circ J.  1988 Dec;18(4):553-558. 10.4070/kcj.1988.18.4.553.

The Role of Pulmonary Circulation in the Metabolism of Atrial Natriuretic Factor in Man

• Seo JD
• Kim HS
• Park SW
• Ryu KH
• Kim CH
• Oh BH
• Park YB
• Cho BY
• Choi YS
• Lee YW

• KMID: 2093244
• DOI: http://doi.org/10.4070/kcj.1988.18.4.553

Abstract

To evaluate the role pulmonary capillary in the metabolism of atrial natriuretic factor(ANF), we measured plasma level of immunoreative(IR) ANF in pulmonary artery, pulmonary vein, left atrium and aorta simultaneously in 7 cardiac patients with patent with foramen ovale without shunt and 8 cardiac patients with atrial septal defect(ASD) with only left to right shunt during cardiac catheterization. Plasma level of IR-ANF in pulmonary vein was significantly lower to be involved in the metabolism of ANF and that ANF secreted by left atrial myocardium is mainly drained through coronary sinus into right atrial cavity rather than directly into left atrial cavity through thebesian vein.

Keyword

Atrial natriuretic factor; Pulmonary circulation

MeSH Terms

Aorta
Atrial Natriuretic Factor*
Capillaries
Cardiac Catheterization
Cardiac Catheters
Coronary Sinus
Foramen Ovale
Heart Atria
Humans
Metabolism*
Myocardium
Plasma
Pulmonary Artery
Pulmonary Circulation*
Pulmonary Veins
Veins
Atrial Natriuretic Factor