Korean J Anesthesiol.  2014 Mar;66(3):240-243. 10.4097/kjae.2014.66.3.240.

Epidural hematoma after thoracic epidural analgesia in a patient treated with ketorolac, mefenamic acid, and naftazone: a case report

• Jeon DG
• Song JG
• Kim SK
• Kim J

• KMID: 2092452
• DOI: http://doi.org/10.4097/kjae.2014.66.3.240

Abstract

A 26-year-old male undergoing thoracotomy and bleeding control received a preoperative thoracic epidural for postoperative analgesia. On the fifth postoperative day, paralysis of both lower limbs occurred and urgent magnetic resonance imaging showed massive anterior epidural hematoma. During laminectomy and decompression, platelet dysfunction was diagnosed and preoperative non-steroidal anti-inflammatory drugs medications were supposed to the cause of platelet dysfunction. After infusion of ten units of platelet concentrate, coagulopathy was improved. We should be more careful to drugs with antiplatelet effect when using regional analgesia.

Keyword

Epidural hematoma; Ketorolac; Mefenamic acid; Naftazone; Platelet function

MeSH Terms

Adult
Analgesia
Analgesia, Epidural*
Blood Platelets
Decompression
Hematoma*
Hemorrhage
Humans
Ketorolac*
Laminectomy
Lower Extremity
Magnetic Resonance Imaging
Male
Mefenamic Acid*
Paralysis
Thoracotomy
Ketorolac
Mefenamic Acid