Korean J Anesthesiol.  1999 Apr;36(4):638-644. 10.4097/kjae.1999.36.4.638.

The Effects of Perfusion Variables on the Neurologic Sequelae in the Infants Who had Arterial Switch Operation Using Continuous Flow Cardiopulmonary Bypass

• Kim CS
• Kim HS
• Oh JI

• KMID: 2091381
• DOI: http://doi.org/10.4097/kjae.1999.36.4.638

Abstract

BACKGROUND: Neurologic sequelae of open heart surgery for congenital heart disease were related with preexisting brain lesion as well as intraoperative causes. These causes are microemboli, blood flow, and blood distribution.
METHODS
This study was designed to examine neurologic sequelae and postoperative course in patients with arterial switch operation using continuous flow cardiopulmonary bypass through retrospective chart review.
RESULTS
Of 22 patients 4 had neurologic sequelae. Cooling rate, extubation time, and duration of ICU admission and hospital admission were statistically different between the patients with neurologic sequelae or not. Patients with neurologic sequelae had more rapid cooling rate and longer duration of intubation, ICU stay, and hospital admission than patients without neurologic sequelae.
CONCLUSIONS
Cooling rate (time to lower 1oC body temperature) is the only factor among perfusion variables to affect on neurologic sequelae. Neurologic complications make it longer to wean the mechanical ventilation, and to stay at ICU and hospital.

Keyword

Complications, neurologic sequelae; Heart, cardiopulmonary bypass; Surgery, arterial switch operation

MeSH Terms

Brain
Cardiopulmonary Bypass*
Heart Defects, Congenital
Humans
Infant*
Intubation
Perfusion*
Respiration, Artificial
Retrospective Studies
Thoracic Surgery