Korean J Anesthesiol.  1992 Jun;25(3):509-514. 10.4097/kjae.1992.25.3.509.

The Relationship between Blood Prssure , Heart Rate and Plasma Level of Catecholamine Concentration

• Kim CS
• Kang CH
• Kim KW

• KMID: 2090708
• DOI: http://doi.org/10.4097/kjae.1992.25.3.509

Abstract

To evaluate the relationship between depth of anesthesia and plasma catecholamine concentration, the authors measured blood pressure(systolic, diastolic, mean), heart rate and plasma concentration of epinephrine and norepinephrine at varying condition of no anesthesia, under anesthesia and after stimulation. The subjects were 30 ASA class 1 surgical patients, aged from 20 to 40 years. Patients were given thiopental(4 mg/kg) and vecuronium(0.1 mg/kg) for induction and intubation. After 5 minutes controlled respiration with 100% oxygen, baseline measurements were taken. Measurements after 20 minutes maintenance with 1.7 vol % enflurane by end tidal concentration and measurement after skin incision were taken. Systolic pressure were 143.5+/-16.7, 107.6+/-15.0, 130.4+/-13,1lmmHg), and heart rate 115. 5+/-15.2, 85.1 +/-l5.3, 104.5+/-12.7(beat/min), plasma epinephrine concentration 93.6+/-48.4, 78.2+/-33.2, 77.0+/-23.5(ng/L), plasma norepinephrine concentration 451.6+/-154.7, 410+/-139.0, 376.7+/-104.3(ng/L), respectively. Systolic, diastolic and mean blood pressure showed significant change(p<0.05) but heart rate and plasma concentration of epinephrine and norepinephrine showed no significant changes.

Keyword

Enflurane; MAC; Catecholamine

MeSH Terms

Anesthesia
Blood Pressure
Enflurane
Epinephrine
Heart Rate*
Heart*
Humans
Intubation
Norepinephrine
Oxygen
Plasma*
Respiration
Skin
Enflurane
Epinephrine
Norepinephrine
Oxygen