Korean J Blood Transfus.  2010 Aug;21(2):165-170.

A Case of Mild Hemolytic Disease of the Fetus and Newborn - The First Case of Anti-Di(b) Identified on Prescreening Test during Pregnancy -

• Choi JW
• Kim MJ
• Kim MH
• Park JR
• Kim HO

Abstract

The Di(a+b-) phenotype is extremely rare among Caucacians and mostly confined to mongoloids. The clinical significance of anti-Di(b) is incompletely recognized. The authors report here a mild case of hemolytic disease of the fetus and newborn (HDFN) due to anti-Di(b). The mother was Di(a+b-) with anti-Di(b), which was detected by antenatal screening. She delivered a Di(a+b+) infant with a positive direct antiglobulin test and mild hemolytic disease. The infant was treated by phototherapy and subsequently recovered without the need for exchange transfusion. We suggest that the screening program as routine prenatal care is necessary.

Keyword

Anti-Di(b); Hemolytic disease of a fetus and newborn; Antenatal screening

MeSH Terms

Coombs Test
Fetus
Humans
Infant
Infant, Newborn
Mass Screening
Mothers
Phenotype
Phototherapy
Pregnancy
Prenatal Care
Prenatal Diagnosis