Patch Test of Cosmetic Cleansers for the Determining Optimum Concentration

Park, Tae Ho; Jeong, Moon Chul; Yoo, Jae Hak; Kim, Kea Jeung

Abstract

BACKGROUND: Cosmetic cleansers are most widely used to remove makeup and sometimes cause allergic or irritation contact dermatitis. We can patch test soaps or shampoos as 2% concentration, but cleansers have been not determined for the concentration by patch test yet.
OBJECTIVE
The objectives of this study were to determine the concentration of cosmetic cleansers for patch test.
METHODS
The skin responses to patch testing with variable cleansers in different concentrations were measured by visual scoring, spectrometer, evaporimeter and corneometer.
RESULTS
The results of the studies were summarized as follows; 1. The cream type and lotion type cleansers showed no skin responses. 2. The skin response of foam type cleansers showed that the one had statistical significance between 2% and 5%, and the other had 5% and 10% concentration. 3. The skin response of gel type cleansers showed statistical significance between 5% and 10% concentration. 4. Through correlation analysis, we found that the evaluation of the evaporimeter or corneometer were not related to the visual measurement.
CONCLUSIONS
We suggest that cosmetic cleansers of water, lotion and cream type can be tested as is(100%), and foam type cleansers with 2%, and gel type should be tested with 5% concentration.