Korean J Dermatol.
2000 Feb;38(2):249-253.
A Case of Cutaneous Metastatic Ewing's Sarcoma
- Affiliations
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- 1Department of Dermatology, College of Medicine, Ewha Womans University
Seoul, Korea.
Abstract
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Ewing's sarcoma is a highly anaplastic, small round cell tumor, primarily arising in
the intramedullary portion of the bone, and metastasis is common. Its origin is unknown.
We describe a case of cutaneous metastatic Ewing's sarcoma in the pubic area in a
23-year-old female, who had been diagnosed as having Ewing's sarcoma of the pelvic
bone three years ago, and treated by wide excision, chemotherapy and radiation therapy.
Histopathologic examination of her nodular lesion revealed a tumor of small round cells
whose membranes were positive for CD99. She was managed by conservative treatment but
expired one month later. To our knowledge, Ewing's sarcoma metastatic to the skin has
not been reported previously in the world. This case supports the neuroectodermal origin
of this tumor and that cutaneous metastasis of this tumor is a hallmark of grave prognosis.