Korean J Dermatol.  2000 Jan;38(1):1-14.

Dermatological Complications due to Vaccination

• Ahn SK
• Ahn HJ

Abstract

Vaccination is defined as the introduction of vaccine into the body for the purpose of inducing immunity. Vaccine contain many antigens, e.g., active antigen in DTP, tissue culture fluid in the suspension of vaccine, aluminum complexes in MMR, preservatives, anti-infectives, and antibiotics which induce many allergic reactions. B.C.G vaccine induce specific and nonspecific dermatological complications on inoculation site or out of vaccination. DPT or TT vaccine induce infection site granuloma due to aluminum on inoculation site, angiolymphoid hyperplasia with eosinophilia, and livedoid skin necrosis. Hepatitis B vaccine can induce many dermatological complications, e.g., urticaria and angioedema, erythema nodosum, systemic lupus erythematosus, lichen planus and thrombocytopenic purpura. Gianoti-Crosti syndrome is caused by MMR vaccine and influenza vaccine. Sweet's syndrome and acute exanthematous pustular dermatitis are developed after pnuemococcal vaccintation. Herpes zoster can be developed after chicken pox vaccination. Erythema and edema can be developed after injection of botulinum toxin. Benign and malignant tumor can be induced by various vaccination, too.

Keyword

Dermatological complication; Vaccination

MeSH Terms

Aluminum
Angioedema
Angiolymphoid Hyperplasia with Eosinophilia
Anti-Bacterial Agents
Botulinum Toxins
Chickenpox
Dermatitis
Edema
Erythema
Erythema Nodosum
Granuloma
Hepatitis B Vaccines
Herpes Zoster
Hypersensitivity
Influenza Vaccines
Lichen Planus
Lupus Erythematosus, Systemic
Measles-Mumps-Rubella Vaccine
Necrosis
Purpura, Thrombocytopenic
Skin
Sweet Syndrome
Urticaria
Vaccination*
Aluminum
Anti-Bacterial Agents
Botulinum Toxins
Hepatitis B Vaccines
Influenza Vaccines
Measles-Mumps-Rubella Vaccine