Korean J Gastrointest Endosc.  2008 Nov;37(5):374-379.

Three Cases of Colonic Pseudolipomatosis Induced by Endoscope Disinfectant

Affiliations
  • 1Department of Internal Medicine, Digestive Disease Research Institute, Institute of Wonkwang Medical Science, Wonkwang University College of Medicine, Iksan, Korea. wms89@hanmail.net
  • 2Department of Pathology, Wonkwang University College of Medicine, Iksan, Korea.
  • 3Department of Internal Medicine,Eulji University College of Medicine, Seoul, Korea.

Abstract

Colonic pseudolipomatosis is a benign condition that is caused by mechanical trauma during an endoscopic procedure or by disinfectant colitis. It is characterized by empty vacuoles that are similar to the adipocyte in the lamina propria on histology and whitish plaques that are seen endoscopy. The prevalence of pseudolipomatosis is relatively low due to the lack of clinical experience and there have been no Korean reports about colonic pseudolipomatosis with the typical endoscopic findings. We report here on three cases of colonic pseudolipomatosis that was caused by endoscope disinfectant (paracetic acid). Typical whitish plaques were observed during the colonoscopic procedures in all 3 cases. In one case, whitish plaques appeared before our eyes immediately after the sudden appearance of whitish foamy fluid when the water button was depressed. H&E stain revealed empty vacuoles in the lamina propria and immunohistochemical staining showed no expression of CD31, CD34 and s-100. There were no symptoms related to these lesions in our cases.

Keyword

Pseudolipomatosis; Colon; Endoscope disinfectant; Paracetic acid

MeSH Terms

Adipocytes
Colitis
Colon
Endoscopes
Endoscopy
Eye
Mucous Membrane
Prevalence
Vacuoles
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