Korean J Nephrol.  2011 May;30(3):292-301.

Comparison of Vascular Calcification Scores on Plain Radiographs to Predict Coronary Artery Disease According to Dialysis Modality

Affiliations
  • 1Department of Internal Medicine, Dong-A University College of Medicine, Busan, Republic of Korea. anws@dau.ac.kr
  • 2Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, Republic of Korea.
  • 3Department of Radiology, Dong-A University College of Medicine, Busan, Republic of Korea.
  • 4Medical Science Research Center, Dong-A University College of Medicine, Busan, Republic of Korea.

Abstract

PURPOSE
Vascular calcification (VC) scores on simple plain radiographic films are known to be associated with coronary artery disease (CAD) in hemodialysis (HD) patients. However, there is no report comparing VC scores on plain radiographic films according to dialysis modality. We hypothesized that there are some differences of VC scores on plain radiographs for the assessment of CAD according to dialysis modality.
METHODS
We recruited 78 peritoneal dialysis (PD) patients and compared to 61 HD patients. We defined significant VC as any one finding among the abdominal aortic calcification (AAC) score > or =5, VC score of the hands and pelvis > or =3, or medial artery calcification of the feet on plain radiographs.
RESULTS
The prevalence of CAD and significant VC were not different according to dialysis modality. Every VC score on the plain radiographs was highly correlated with each other, but VC evaluation on plain radiographs by single method overlooked nearly 30% of other significant VC sites in PD and HD patients. AAC score was most useful method for the prediction of CAD as a single VC scoring method. There was no association between VC of the feet and CAD in PD patients. Lower high density lipoprotein cholesterol was associated with significant VC on plain radiograph in PD patients.
CONCLUSION
Significant VC formation on plain radiographs was not different according to dialysis modality. It is helpful to check several plain radiographs for the decision of CAD evaluation and not overlooking significant VC in both HD and PD patients.

Keyword

Vascular calcification; Radiography; Coronary artery disease; Dialysis

MeSH Terms

Arteries
Cholesterol
Cholesterol, HDL
Coronary Artery Disease
Coronary Vessels
Dialysis
Foot
Hand
Humans
Lipoproteins
Pelvis
Peritoneal Dialysis
Prevalence
Renal Dialysis
Research Design
Vascular Calcification
X-Ray Film
Cholesterol
Cholesterol, HDL
Lipoproteins
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