Korean J Nephrol.  2003 Nov;22(6):744-748.

Primary Sjogren's Syndrome with Renal Pseudolymphoma Featuring Interstitial Nephritis

Affiliations
  • 1Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul, Korea. whuh@smc.samsung.co.kr
  • 2Department of Pathology, Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul, Korea.
  • 3Department of Radiology, Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul, Korea.

Abstract

A 65 year-old woman with Sjogren's syndrome was found to have renal mass and acute renal failure. Immunopathologic analysis of renal biopsy specimens showed polyclonal lymphocytic interstitial infiltration. Gene rearrangement study of T cell receptor showed a polyclonal pattern. The degree of azotemia and the size of pseudolymphoma diminished dramatically with steroid therapy. This is a case of proven pseudolymphoma that was found as renal mass in Sjogren's syndrome.

Keyword

Sjogren's syndrome; Pseudolymphoma; Interstitial nephritis; Acute renal failure

MeSH Terms

Acute Kidney Injury
Aged
Azotemia
Biopsy
Female
Gene Rearrangement
Humans
Nephritis, Interstitial*
Pseudolymphoma*
Receptors, Antigen, T-Cell
Sjogren's Syndrome*
Receptors, Antigen, T-Cell
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