Korean J Obstet Gynecol.  2012 Aug;55(8):596-600. 10.5468/KJOG.2012.55.8.596.

Postirradiation malignant fibrous histiocytoma of the vulva and vagina following recurrent cervix cancer

• Yun HG
• Kim JH
• Lee TH

• KMID: 2078112
• DOI: http://doi.org/10.5468/KJOG.2012.55.8.596

Abstract

We describe here the case of a 65-year-old women presenting with a hemorrhagic tumor around the anterior vaginal wall and vulva. She was diagnosed with malignant fibrous histiocytoma from the findings of cytological analysis of biopsied surface tissue, histopathologic analysis of biopsied, and immunohistochemical staining. In her past history, twenty years ago, she was diagnosed with cervical cancer, staging Ib and received surgical treatment and chemotherapy. Ten years ago, she received radiotherapy because of recurrence of cervical cancer in vaginal vault. After surgical excision for malignant fibrous histiocytoma, we recommended chemotherapy but she refused. After 24 months from initial diagnosis, she died.

Keyword

Malignant fibrous histiocytoma; Radiotherapy; Recurrent cervical cancer

MeSH Terms

Aged
Cervix Uteri
Female
Histiocytoma, Malignant Fibrous
Humans
Recurrence
Uterine Cervical Neoplasms
Vagina
Vulva

Figure

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  Fig. 1 Preoperative appearance of malignant fibrous histiocytoma was noted around the urethral orifice, urethral stenosis due to pressed the mass. Size 3×4 cm.

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  Fig. 2 Gross finding, including mass removed, appearance of anterior vaginal wall and vulva that are removed.

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  Fig. 3 Microscopic findings of malignant fibrous histiocytoma show fascicles of plump spindle cells in a swirling (storiform) pattern, typical but not pathognomic pattern of this neoplasm. (A) H&E, ×100. (B) Vitamin, ×100.

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