Korean J Obstet Gynecol.  2007 Jun;50(6):887-892.

Prognostic factors in recurrent cervical cancer patients with pulmonary metastasis

• Lyu MO
• Kim HY
• Yoon JH
• Chang SJ
• Lee JP
• Chang KH
• Ryu HS
• Kim JH

Abstract

OBJECTIVE
To characterize prognostic factors in patients with pulmonary metastasis in recurrent cervical cancer.
METHODS
The records of 2,042 patients treated for cervical cancer from 1994 to 2004 at two institutions were retrospectively reviewed. Twenty-five (1.04%) patients had pulmonary lesions consistent with metastatic cervical cancer. The data were analyzed retrospectively and reviewed for patient characteristics.
RESULTS
Patients were treated with chemotherapy, radiotherapy only, chemoradiotherapy, surgery, and conservative treatment. There were no significant differences in survival rates between each treatment method (p=0.3410). Mean survival after treatment of pulmonary metestasis was 23 months. Histologic type, lymph node metastasis, other organ metastasis, and pretreatment SCC level were not significant prognostic factors, but FIGO stage (p=0.039) and disease-free interval (p=0.033) were significant factors.
CONCLUSION
This study revealed that FIGO stage and disease-free interval were independent prognostic factors of pulmonary metestasis in recurrent cervical cancer.

Keyword

Cervical cancer; Pulmonary metastasis; Prognosis

MeSH Terms

Chemoradiotherapy
Drug Therapy
Humans
Lymph Nodes
Neoplasm Metastasis*
Prognosis
Radiotherapy
Retrospective Studies
Survival Rate
Uterine Cervical Neoplasms*