Korean J Obstet Gynecol.
2002 Nov;45(11):2035-2038.
A Case of Holoprosencephaly
- Affiliations
-
- 1Department of Obstetrics and Gynecology, College of Medicine, Inje University, Seoul Paik Hospital, Seoul, Korea.
- 2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea.
Abstract
- Holoprosencephaly is a rare developmental defect due to incomplete cleavages of the prosencephalon during the third week of fetal development. It was associated with chromosomal anomalies, genetic syndrome, teratogen, or genetic disorder of non-syndromic HPE. Early antenatal detection of holoprosencephaly was done by high resolution ultrasonography. According to its severity and prognosis, it was capable of proper treatment of holoprosencephaly. We report one case of holoprosencephaly with a brief review of the literature
