Korean J Obstet Gynecol.  2002 Sep;45(9):1606-1610.

De novo Fetal Chromosomal Abnormalities after Assisted Reproductive Technology

• Ahn KH
• Lee KO
• Joo JK
• Shin BS
• Choi OH

Abstract

We experienced two cases of de novo fetal chromosomal abnormalities after assisted reproductive technology (ART): One case was reciprocal translocation 46,XX,t(6;14)(p21.3;q12) after intracytoplasmic sperm injection and embryo transfer (ICSI-ET) and the other case was 46,X,iso(Xq) after in vitro fertilizaton and embryo transfer (IVF-ET), both were diagnosed prenatally by amniocentesis and postnatally cord blood culture. We report these cases with a brief review of literatures.

Keyword

ART (IVF, ICSI); De novo chromosomal abnormality; 46,XX,t(6;14)(p21.3;q12); 46,X,iso(Xq)

MeSH Terms

Amniocentesis
Chromosome Aberrations*
Embryo Transfer
Fetal Blood
Reproductive Techniques, Assisted*
Sperm Injections, Intracytoplasmic