Korean J Obstet Gynecol.
2002 Jul;45(7):1214-1217.
Toremifene-associated endometrial polyp: A case report and review of the literature
- Affiliations
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- 1Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Seoul, Korea.
- 2Department of pathology, Soonchunhyang University College of Medicine, Seoul, Korea.
Abstract
- Antiestrogens have been widely used in the treatment of breast cancer patients. Although tamoxifen is one of the most prevalent antiestrogens, some reported its hepatocarcinogenic effects and the long-term treatment may increase the risk of endometrial and gastrointestinal cancer. Toremifene is an interesting new antiestrogen and have a similar antitumor efficacy as tamoxifen, with less side-effect including less uterotrophic effect compared to tamoxifen, in mice. we report a case of endometrial polyp which were associated with toremifene use, in postmenopausal woman with breast cancer, with a brief review of literature.
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