Korean J Obstet Gynecol.  2001 Sep;44(9):1719-1723.

A Case of Complete Remission by Combination Chemotherapy with BEP Regimen after Operation in Endodermal Sinus Tumor of Ovary

• Choi YR
• Lee JJ
• Song JH
• Jeon SC
• Kang JH
• Cho DH
• Lee MS

Abstract

Endodermal sinus tumor (EST) has also been referred to as yolk sac carcinoma because they are derived from the primitive yolk sac. These lesions are the third most frequent malignant germ cell tumor of the ovary. Patient with EST have a median age of 18 years, but approximately one third of the patients are premenarchal at the time of initial presentation. Abdominal and/or pelvic pain is the most frequent presenting symptom, most EST secrete AFP. Radical surgery has not been helpful, but recent advances in treating the EST of the ovary with the combination chemotherapy after unilateral salpingo-oophorectomy result in improvement of the prognosis. We had experienced a case of endodermal sinus tumor of 36 years old woman. So, we report this case with brief review of the literature.

Keyword

EST; BEP

MeSH Terms

Adult
Drug Therapy, Combination*
Endoderm*
Endodermal Sinus Tumor*
Female
Humans
Neoplasms, Germ Cell and Embryonal
Ovary*
Pelvic Pain
Prognosis
Yolk Sac