Korean J Obstet Gynecol.  1997 Jul;40(7):1546-1550.

Treatment of Cervical Pregnancy with Methotrexate

Affiliations
  • 1Department of Obstetrics and Gynecology, Eul-ji General Hopspital, Seoul, Korea.

Abstract

Cervical pregnancy is one of most rare form of ectopic pregancy in which the blastocyst implants within the cervical canal below the internal os of uterine cervix. Most cervical pregnancy result in early spontaneous abortion, complicated by severe hemorrhage frm the eroded blood vessels within the cervix. Because of fear of rofuse hemorrhage, abdominal hysterectomy has been historically considered the standard therapy. However, a number of new therapies have been aimed at uterine preservation, conservative treatment is highly desirable for young women who want to be pregnancy in the future. Methotrexate has been utilized recently for the successful management of tubal, interstitial, and cervical ectopic gestations. We report a case of a cervical preganncy that was successfully managed with methotrexate and leucovorine.

Keyword

Cervical pregnancy; methotrexate; Leucovorine

MeSH Terms

Abortion, Spontaneous
Blastocyst
Blood Vessels
Cervix Uteri
Cytochrome P-450 CYP1A1
Female
Hemorrhage
Humans
Hysterectomy
Leucovorin
Methotrexate*
Pregnancy*
Cytochrome P-450 CYP1A1
Leucovorin
Methotrexate
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