Korean J Pathol.
1999 Sep;33(9):745-750.
Symptomatic Graular Cell Tumor Involving Intra- and Suprasellar Area: A case report
- Affiliations
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- 1Department of Pathology, Yonsei University Medical College, Seoul 120-752, Korea.
- 2Department of Neurosurgery, Yonsei University Medical College, Seoul 120-752, Korea.
Abstract
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Symptomatic parasellar granular cell tumor is a very rare tumor. To the best of
our knowledge, 43 cases was be found in the English literatures. We recently
experienced a case of a parasellar granular cell tumor in a 61-year-old female who had
bilateral temporal hemianopsia and severe panhypopituitarism. The tumor was composed
of diffuse sheets of polygonal cells with abundant eosinophilic PAS positive granular
cytoplasm. In the immunohistochemical and ultrastructural examinations, the tumor failed
to show any evidence of Schwann cell or glial differentiation. These findings suggest
that granular cell tumor has heterogenous cell types of origin.