Korean J Perinatol.
2002 Mar;13(1):3-8.
Postnatal Outcome of Neonatal Thyroid Function Born to Mother with Thyroid Dysfunction
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea.
Abstract
OBJECTIVE
The health of the mother during pregnancy has a great effect on the fetus and the neonate. This research was conducted to determine what effect thyroid disease control and administration of medication during pregnancy had on the thyroid function of the newborn.
METHODS
Clinical observation was conducted by examining the history, medical records, and neonatal thyroid function tests and records of 79 infants born to 79 mothers with thyroid dysfunction in the OBGY department at the Kyung Hee Medical Center between January of 1995 to December of 2000.
RESULTS
Of the 79 research subjects, 55 infants were born to mother with hyperthyroidism(Group A)(70%), and 24 infants were born to mother with hypothyroidism(Group B)(30%). Infants born to mothers maintained normal thyroid function during pregnancy(Group I) are 52 cases(66%), undetermined state(Group II) are 16 cases(20%), and thyroid dysfunction(Group III) are 11 cases(14%). The accompanying diseases were demonstrated. There were no difference in clinical characteristics of the infants between Group A and Group B. 5 infants in Group 1(9%), 7 infants in Group 2(Group 43%), 9 infants in Group 3(82%) demonstrated thyroid dysfunction. 76% of the neonates with thyroid dysfunction were born from mothers with a history of intake of medication(Table 4). Of the total of 79 infants born to mothers with thyroid dysfunction, only 1 neonate developed hyperthyroidism and others returned to normal thyroid function.
CONCLUSION
Through this research, we were able to learn that in mothers with thyroid dysfunction during pregnancy the level of control of thyroid function and the intake of medication has significantly effect on the neonate.
