Korean J Urol.  2014 Nov;55(11):732-736. 10.4111/kju.2014.55.11.732.

Complications of Transrectal Ultrasound-Guided Prostate Biopsy: Impact of Prebiopsy Enema

• Kam SC
• Choi SM
• Yoon S
• Choi JH
• Lee SH
• Hwa JS
• Chung KH
• Hyun JS

• KMID: 2069915
• DOI: http://doi.org/10.4111/kju.2014.55.11.732

Abstract

PURPOSE
Transrectal ultrasound (TRUS)-guided biopsy of the prostate is usually safe. However, some patients are hospitalized owing to complications from TRUS biopsy. We identified the risk factors for complications and effective preventive measures for treating complications after TRUS biopsy.
MATERIALS AND METHODS
Medical records and radiological images of 1,083 patients who underwent TRUS biopsy of the prostate over 10 years in Gyeongsang National University Hospital were examined retrospectively to investigate the correlation between complications after TRUS biopsy and preventive antibiotics, prebiopsy enema, number of biopsy cores, and pathological findings.
RESULTS
Complications occurred in 69 patients (6.4%). The complication rates of the 1,008 patients who received antibiotics and the 75 patients who did not were 6.3% and 8.0%, respectively (p=0.469). Complication rates of the pre-biopsy enema group (n=658) and the group without prebiopsy enema (n=425) were 4.7% and 8.9%, respectively (p=0.007). Complication rates of the 6-core biopsy group (n=41) and the 12-core biopsy group (n=955) were 7.3% and 6.3%, respectively (p=0.891). Complication rates of the prostate cancer group (n=306) and the no prostate cancer group (n=713) were 6.2% and 6.6%, respectively (p=0.740).
CONCLUSIONS
A prebiopsy enema was associated with a reduced risk of complications after TRUS biopsy. Preventive antibiotics, number of biopsy cores, and pathological findings did not significantly influence the complication rate.

Keyword

Biopsy; Complications; Enema; Prostate

MeSH Terms

Aged
*Endosonography
Enema/*methods
Humans
Image-Guided Biopsy/*adverse effects/methods
Incidence
Male
Prostatic Neoplasms/*pathology
Prostatitis/epidemiology/etiology/*prevention & control
Rectum
Republic of Korea/epidemiology
Retrospective Studies
Risk Factors
Syncope, Vasovagal/epidemiology/etiology/*prevention & control
Urinary Retention/epidemiology/etiology/*prevention & control

Figure

• 

  FIG. 1 Complications of transrectal ultrasound (TRUS)-guided prostate biopsy and the number of patients admitted. AP, acute prostatitis; HR, hematoma retention; VS, vasovagal syncope; NHR, nonhematoma retention; Cx, complication; Adm, admission.

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