J Korean Neurosurg Soc.  1997 Jul;26(7):1003-1006.

Familial Intracranial Aneurysm

• Soh JN
• Oh SM
• Shin DI
• Park SH

Abstract

The familial occurrence of intracranial aneurysms, defined as the presence of one or more aneurysms in two or more blood relatives, is well established and is relatively rare. The pattern of inheritance in these families is not usually known. The authors report one case of familial intracranial aneurysm, without specific genetic disorder, occurring during a recent six-month period in three of five siblings. Two of these were females, aged 36 and 39, and the other was a 40-year-old male. Two of these patients had ruptured aneurysms, but in the other, the aneurysm was unruptured. All were treated successfully by clipping of the aneurysmal neck, without any neurological deficits. The authors describe their experience of a rare familial intracranial aneurysm, occurring in the absence of a specific genetic disorder, and review the literature concerning this type of aneurysm.

Keyword

Familial intracranial aneurysm; Subarachnoid hemorrhage

MeSH Terms

Adult
Aneurysm
Aneurysm, Ruptured
Female
Humans
Intracranial Aneurysm*
Male
Neck
Siblings
Subarachnoid Hemorrhage
Wills