J Korean Neurol Assoc.
1999 Sep;17(5):735-740.
One case of Subacute Sensory Neuropathy Associated with Primary Sjogren's Syndrome
- Affiliations
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- 1Department of Neurology, National Medical Center, Seoul, Korea.
- 2Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Subacute sensory neuropathies associated with primary Sjogren's syndrome have been reported rarely. We describe a woman with primary Sjogren's syndrome who developed a widespread, pure sensory neuropathy with a subacute onset. An electrophysiological study showed the typical absence or decreased amplitude of sensory nerve action potentials (SNAPs). A sural nerve biopsy showed a loss of large myelinated fibers and axonal degeneration without inflammation. The clinical course of long-standing subacute sensory neuropathy, the biopsy-documented axonal degeneration, and the neurophysiological findings suggest involvement of the dorsal root ganglia.
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