J Korean Neurol Assoc.  1999 Sep;17(5):735-740.

One case of Subacute Sensory Neuropathy Associated with Primary Sjogren's Syndrome

Affiliations
  • 1Department of Neurology, National Medical Center, Seoul, Korea.
  • 2Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Subacute sensory neuropathies associated with primary Sjogren's syndrome have been reported rarely. We describe a woman with primary Sjogren's syndrome who developed a widespread, pure sensory neuropathy with a subacute onset. An electrophysiological study showed the typical absence or decreased amplitude of sensory nerve action potentials (SNAPs). A sural nerve biopsy showed a loss of large myelinated fibers and axonal degeneration without inflammation. The clinical course of long-standing subacute sensory neuropathy, the biopsy-documented axonal degeneration, and the neurophysiological findings suggest involvement of the dorsal root ganglia.

Keyword

Peripheral neuropathy; Sjogren's syndrome; Sensory neuropathy; Dorsal root ganglia

MeSH Terms

Action Potentials
Axons
Biopsy
Female
Ganglia, Spinal
Humans
Inflammation
Myelin Sheath
Peripheral Nervous System Diseases
Sjogren's Syndrome*
Sural Nerve
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