J Korean Geriatr Psychiatry.
2001 Jun;5(1):50-57.
Reliability and Analysis of Symptom Category Scores of the Behavior Pathology in Alzheimer's Disease Rating Scale, Korean Version(BEHAVE-AD-K)
- Affiliations
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- 1Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. suhgh@chollian.net
- 2Department of Psychiatry, Chunchon Sacred Heart Hospital, Hallym University College of Medicine, Chunchon, Korea.
- 3Department of Psychiatry, Catholic University of Taegu-Hyosung School of Medicine, Taegu, Korea.
- 4Incheon Eunhye Hospital, Incheon, Korea.
- 5Department of Psychiatry, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
Abstract
OBJECTIVE
The aims of this study were to (1) validate the inter-rater reliability of the BEHAVE-AD, Korean version, to (2) analyze the quantitative relationship between severity of Alzheimer's disease (AD) and mean scores on each of the BEHAVE-AD categories and mean total BEHAVE-AD score.
DESIGN: Cross-sectional study of geriatric patients with AD evaluated at a mental hospital for the elderly.
SAMPLE: Fifty-two consecutive patients diagnosed with probable Alzheimer's disease (AD) according to NINCDS-ADRDA diagnostic criteria.
RESULTS
In reliability study, significant correlations were obtained for all BEHAVE-AD symptoms category scores and for mean total BEHAVE-AD scores. Analysis of BEHAVE-AD scores as a function of disease severity demonstrated a non-linear relationship between severity of behavioral symptoms and the global and cognitive advance of AD. Score analysis of the BEHAVE-AD indicates that these behavioral disturbances become most severe in the moderate and moderately severe stages of AD.
CONCLUSION
All the results proved the cross-cultural validity and reliability of the BEHAVE-AD, Korean version. Furthermore, these results have implications for the methodology of pharmacological trials of putative cognitive enhancer compounds in AD.