J Korean Assoc Maxillofac Plast Reconstr Surg.  2013 Mar;35(2):130-135.

Primary Intraosseous Squamous Cell Carcinoma Arising from Odontogenic Cyst: A Case Report

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Institute of Oral Bio-Science, Brain Korea 21 Project, Korea. omfskso@jbnu.ac.kr
  • 2Research Institute of Clinical Medicine, Chonbuk National University, Biomedical Research Institute, Chonbuk National University Hospital, Korea.

Abstract

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare form arising within the jaws. PIOSCC is not related to the oral mucosa, presumably developing from remnants of the odontogenic epithelium. Because odontogenic cyst epithelium often transforms malignantly into PIOSCC, it could be misdiagnosed as odontogenic cyst based on a relatively ill-defined radiolucent lesion. Therefore, definite diagnosis is established from histological examination of biopsy samples taken during cyst enucleation in many cases. The present study is reported with a case of patient complaining of discomfort on his mandible. He was diagnosed as a putative dentigerous cyst and underwent a cyst enucleation treatment. After definite diagnosis as PIOSCC was established based on histologic findings, partial mandible resection and mandible reconstruction were performed. Up to the present, 10 months follow up of the patient showed satisfactory healing without recurrence and abnormal findings; thereby, we are reporting this case with literature review.

Keyword

Squamous cell carcinoma; Odontogenic cysts; Mandible

MeSH Terms

Biopsy
Carcinoma, Squamous Cell
Dentigerous Cyst
Epithelium
Follow-Up Studies
Humans
Jaw
Mandible
Mouth Mucosa
Odontogenic Cysts
Recurrence
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