Obstet Gynecol Sci.  2015 Sep;58(5):409-413. 10.5468/ogs.2015.58.5.409.

Successful pregnancy outcome in a Korean patient with symptomatic Wilson's disease

Affiliations
  • 1Department of Obstetrics and Gynecology, Catholic University of Daegu School of Medicine, Daegu, Korea. bjy2014@cu.ac.kr
  • 2Department of Obstetrics and Gynecology, Kyungpook National University Hospital, Daegu, Korea.

Abstract

Wilson's disease is an inherited disease of copper metabolism leading to the toxic accumulation of copper, primarily in the liver and brain. Although the literature shows successful outcomes after proper treatment, pregnant patients with Wilson's disease still need close monitoring and management. Here, we report the case of a successful pregnancy in a Korean woman with Wilson's disease. A 33-year-old primigravid patient with Wilson's disease visited our antenatal clinic. Of her own volition, she had stopped her medication 2 years earlier. Oral zinc oxide therapy was started, and she was closely monitored throughout her pregnancy. She delivered a healthy female infant weighing 3.13 kg through a cesarean section. After delivery, the clinical course of both the mother and the baby were uneventful. We review crucial points in the treatment and the management dilemmas raised by the patient.

Keyword

Complication; Pregnancy; Wilson's disease; Zinc

MeSH Terms

Adult
Brain
Cesarean Section
Copper
Female
Hepatolenticular Degeneration*
Humans
Infant
Liver
Metabolism
Mothers
Pregnancy
Pregnancy Outcome*
Pregnancy*
Volition
Zinc
Zinc Oxide
Copper
Zinc
Zinc Oxide
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