J Gynecol Oncol.  2009 Mar;20(1):60-62. 10.3802/jgo.2009.20.1.60.

A case of clear cell carcinoma arising from the endometriosis of the paraovarian cyst

• Lee JY
• Im ES
• Kim SW
• Kim H
• Kim YB
• Jeon YT

• KMID: 2055651
• DOI: http://doi.org/10.3802/jgo.2009.20.1.60

Abstract

Malignant transformation of endometriosis is an infrequent complication. Clear cell carcinoma from endometriosis is very rare in the paraovarian cyst. To date no cases have been reported. We report a case of clear cell carcinoma arising from endometriosis of the paraovarian cyst with a brief review of literature.

Keyword

Clear cell carcinoma; Endometriosis; Paraovarian cyst

MeSH Terms

Endometriosis
Female

Figure

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  Fig. 1 Computed tomography shows 16 cm sized huge cystic mass with small solid portion (arrow) in the pelvic cavity.

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  Fig. 2 A unilocular cyst is seen with focal areas of solid papillary growth. The remaining internal lining surface shows areas of hemorrhage.

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  Fig. 3 Scanning of the cyst with low magnification reveals a portion of solid growth. The cyst wall contains a smooth muscle layer and the internal surface is focally lined by cuboidal to columnar epithelium (Hematoxylin-Eosin, original magnification ×10).

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  Fig. 4 Higher power magnification of the solid portion reveals tumor cells with pleomorphic nuclei and eosinophilic or clear cytoplasm arranged in tubular or acinar structures. A hobnail pattern is prominent (Hematoxylin-Eosin, original magnification ×200).

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