Hanyang Med Rev.
2009 Nov;29(4):327-337.
Prevention and Treatment of Bronchopulmonary Dysplasia
- Affiliations
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- 1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. choicw@snu.ac.kr
Abstract
- Despite recent remarkable advances in neonatal medicine, bronchopulmonary dysplasia (BPD) remains a major cause of morbidity and mortality in preterm infants. Due to increased survival of extremely low birth weight infants, the incidence of BPD has increased approximately 30% of extremely low birth weight infants. However, we have not discovered any single highly effective preventive therapy for BPD. This is due to an incomplete understanding of the molecular mechanisms involved in its pathogenesis. In this review, we review the current management strategies for preventing and treating BPD and then briefly propose novel approaches that are being investigated.