Electrolyte Blood Press.  2015 Jun;13(1):22-29. 10.5049/EBP.2015.13.1.22.

Abdominal Obesity and Mortality in Continuous Ambulatory Peritoneal Dialysis Patients

Affiliations
  • 1Division of Nephrology, Department of Internal Medicine, Yanbian University Hospital, Yanji, Jilin Province, China.
  • 2Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. swleemd@inha.ac.kr

Abstract

BACKGROUND
The relationship between abdominal obesity (AO) and mortality in peritoneal dialysis (PD) patients is controversial.
METHODS
The prevalence of AO in 84 PD patients was assessed in a cross-section manner and followed up for 9 years at a single center. AO was defined as a waist circumference (WC) of more than 90 cm in males or more than 80 cm in females. The patients were classified as either with AO(AO group) or without AO(nAO group).
RESULTS
The AO group was older, contained more diabetics, more females, and had higher Charlson comorbidity index (aCCI) scores, BMI, and triglyceride and lower serum creatinine than the non-AO subjects. The follow-up duration was 53.2+/-34.4 months. At the end of the follow-up, eighteen patients (21.4%) were dead; 9 died of cardiovascular causes. The five year survival rate was 40.8%. Kaplan-Meier analysis revealed that both all-cause and cardiovascular-cause mortalities were similar in the AO and nAO groups. Multivariate analysis revealed the presence of AO not to be an independent risk factor of all-cause and cardiovascular-cause mortality.
CONCLUSION
AO itself might not be a risk factor for mortality in PD patients. Nevertheless, further prospective studies with a large number of patients will be needed to prove this.

Keyword

Abdominal obesity; Continuous ambulatory peritoneal dialysis; Mortality; Risk factors; Chronic kidney failure

MeSH Terms

Comorbidity
Creatinine
Female
Follow-Up Studies
Humans
Kaplan-Meier Estimate
Kidney Failure, Chronic
Male
Mortality*
Multivariate Analysis
Obesity, Abdominal*
Peritoneal Dialysis
Peritoneal Dialysis, Continuous Ambulatory*
Prevalence
Risk Factors
Survival Rate
Triglycerides
Waist Circumference
Creatinine
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