Pediatr Allergy Respir Dis.
2000 Mar;10(1):69-74.
Five Cases of Severe Allergic Keratoconjunctivits Not Respond to Treatment
- Affiliations
-
- 1Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea.
- 2Institute of Allergy, College of Medicine, Yonsei University, Seoul, Korea.
- 3Department of Opthalmology, College of Medicine, Yonsei University, Seoul, Korea.
- 4Department of Pediatrics, Ilsan Bokyem Hospital, Ilsan, Korea.
- 5Department of Pediatrics, College of Medicine, Inje University, Ilsan Back Hospital, Kwandong University, Myung-gi Hospital, Ilsan, Korea.
Abstract
- Conjunctivitis of allergic origin is associated with a diversity of clinical presentation. The common features include pronounced itching, a milky conjunctival appearance, a stringy or ropy discharge & papillary hypertrophy of the tarsal conjunctiva in severe cases, and a family history of allergy. The pathogenesis of ocular allergy involves multiple mechanisms, which lead to mast cell degranulation & the release of chemical mediators. The current therapy of ocular allergy involves elimination of the offending allergen, modulation of the immune system, & pharmacologic inhibition of chemical mediators. We are reporting 5 cases of severe allergic keratoconjunctivitis.
