Tuberc Respir Dis.  1999 Aug;47(2):272-273. 10.4046/trd.1999.47.2.272.

A Case Report of the Primary Lung Lymphoma

• Kim YR
• Youn SY
• Yoo KH
• Ahn CM
• Kim HJ
• Jin CJ

• KMID: 2050183
• DOI: http://doi.org/10.4046/trd.1999.47.2.272

Abstract

The primary lymphoma in the lung is very rare. Most of the primary pulmonary lymphomas, which represent 3-4 % of extra-nodal lymphomas, are low-grade B-cell lymphoma. The low-grade B-cell lymphomas progress slowly and the prognosis of these are more favorable than that of the nodal lymphomas. However, high-grade forms progress rapidly with more severe course. The diagnosis of primary pulmonary lymphomas generally relies on the histopathologic findings of lung specimens obtained by surgical excision of the lesions or open-lung biopsy. Recently, less aggressive biopsies(transbronchial, transthoracic) and/or immunocyto -chemical, immunochemical and gene rearrangement studies on materials obtained by bronchoalveolar lavage have been used occasionally. The treatment of the primary pulmonary lymphomas has not been precisely codified. Several clinical data suggest that limited surgery or non -aggressive chemotherapy can provide long-term survival in patients with such slowly developing neoplasm, and demonstrated the need for the development of noninvasive diagnostic methods. In this study, we report a case of high-grade B-cell lymphoma of the lung which was treated with combination chemotherapy.

Keyword

Primary lung lymphoma; High-grade; B-cell; Chemotherapy

MeSH Terms

B-Lymphocytes
Biopsy
Bronchoalveolar Lavage
Diagnosis
Drug Therapy
Drug Therapy, Combination
Gene Rearrangement
Humans
Lung*
Lymphoma*
Lymphoma, B-Cell
Prognosis