Yeungnam Univ J Med.  2006 Dec;23(2):232-239. 10.12701/yujm.2006.23.2.232.

Two Cases of Alopecia Totalis treated with Diphenylcyclopropenone (DPCP) Immunotherapy

Affiliations
  • 1Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. khkim@med.yu.ac.kr

Abstract

Treatments for alopecia areata include topical corticosteroid treatment, corticosteroid intralesional injection, systemic corticosteroid treatment, PUVA(psoralen-UVA) and topical immunotherapy. The therapeutic effects are variable. Alopecia totalis is hard to treat completely. Topical immunotherapy with dinitrochlorobenzene (DNCB), squaric acid dibutyl ester (SADBE) or diphenylcyclopropenone (diphencyprone, DPCP) represents the most accepted therapeutic modality for the treatment of extensive alopecia areata. We report two cases of alopecia totalis treated with DPCP. After DPCP treatment, total scalp hair was completely recovered.

Keyword

Diphenylcyclopropenone (DPCP); Alopecia totalis; Alopecia areata
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