Clin Endosc.  2013 May;46(3):297-300. 10.5946/ce.2013.46.3.297.

Huge Liposarcoma of Esophagus Resected by Endoscopic Submucosal Dissection: Case Report with Video

• Yo I
• Chung JW
• Jeong MH
• Lee JJ
• An J
• Kwon KA
• Rim MY
• Hahm KB

• KMID: 2048938
• DOI: http://doi.org/10.5946/ce.2013.46.3.297

Abstract

Liposarcoma is one of the most common soft tissue sarcomas occurring in adults, but it rarely occurs in the gastrointestinal tract and more uncommonly in the esophagus. To the best of our knowledge, there are only 19 reported cases of esophageal liposarcoma in the literature published in English language up to the year 2008, and they were all treated by surgical methods. Here, we report a case of primary liposarcoma of the esophagus which was treated with endoscopic submucosal dissection (ESD). ESD was well tolerated in this patient, suggesting that it may be a therapeutic option for primary esophageal sarcomas.

Keyword

Esophageal neoplasms; Liposarcoma; Endoscopy

MeSH Terms

Adult
Endoscopy
Esophageal Neoplasms
Esophagus
Gastrointestinal Tract
Humans
Liposarcoma
Sarcoma

Figure

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  Fig. 1 Contrast-enhanced computed tomography scan (A, transverse view; B, coronal view) images demonstrate a tumor (arrowheads) protruding into the esophageal lumen. The large tumor is almost completely obstructing the esophagus.

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  Fig. 2 (A) Esophagogastroduodenoscopy image shows a huge mass with stalk. (B) Endoscopic ultrasonography image shows a submucosal mass located in the posterior wall of upper to mid esophagus. The diameters of the mass were 12.7 and 37.1 mm, respectively.

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  Fig. 3 (A) Esophagogastroduodenoscopy image during endoscopic submucosal dissection. (B) Gross image shows a yellowish, multilobulating mass divided by fibrous septa. (C) Microscopic finding shows a bizarre, big nucleus (arrowhead) suggesting liposarcoma rather than lipoma (H&E stain, ×200).

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  Fig. 4 On esophagogastroduodenoscopy after endoscopic submucosal dissection, there is no evidence of recurrence or metastasis.

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