Ann Pediatr Endocrinol Metab.  2013 Jun;18(2):76-80. 10.6065/apem.2013.18.2.76.

Age at menarche and adult height in girls born small for gestational age

Affiliations
  • 1Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea.
  • 2Department of Pediatrics, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.
  • 3Department of Pediatrics, Hallym University Kangdong Sacred Heart Hospital, Seoul, Korea. ithwang83@hallym.or.kr

Abstract

PURPOSE
The aim of this study was to evaluate the association between birth characteristics based on birth weight for gestational age, timing of menarche and adult height in girls born small for gestational age (SGA).
METHODS
Thirty subjects born from 1988 through 1999 whose birth weight below 10th percentile for their gestational ages were recruited based on hospital chart reviews. The age of each subject at menarche was recorded, and the subject's heights and bone age were assessed.
RESULTS
The adult height of the girls born SGA was significantly lower than the normal adult height and slightly shorter than their target height. The adult height was associated with the birth weight for gestational age. The age at menarche was not different with the menarche timing of the general population.
CONCLUSION
More attention may need to be paid to the growth outcomes of SGA patients whose birth weight is lower for their gestational age than other SGA subjects.

Keyword

Small for gestational age infant; Menarche; Body height

MeSH Terms

Adult
Birth Weight
Body Height
Female
Gestational Age
Humans
Menarche
Parturition

Figure

  • Fig. 1 Distribution of the ages at menarche of the girls born small for gestational age. The mean age at menarche was 11.8±1.2 years.

  • Fig. 2 Birth weights versus the ages at menarche of the girls born small for gestational age. There was no correlation between these two parameters (P=0.099).

  • Fig. 3 Birth weight standard deviation score (SDS) compared with the degree of growth potential reached. There was a positive correlation between these two parameters.


Reference

1. Gardosi J. New definition of small for gestational age based on fetal growth potential. Horm Res. 2006; 65(Suppl 3):15–18. PMID: 16612109.
Article
2. Persson I, Ahlsson F, Ewald U, Tuvemo T, Qingyuan M, von Rosen D, et al. Influence of perinatal factors on the onset of puberty in boys and girls: implications for interpretation of link with risk of long term diseases. Am J Epidemiol. 1999; 150:747–755. PMID: 10512428.
Article
3. Adair LS. Size at birth predicts age at menarche. Pediatrics. 2001; 107:E59. PMID: 11335780.
Article
4. dos Santos Silva I, De Stavola BL, Mann V, Kuh D, Hardy R, Wadsworth ME. Prenatal factors, childhood growth trajectories and age at menarche. Int J Epidemiol. 2002; 31:405–412. PMID: 11980804.
Article
5. Albertsson-Wikland K, Wennergren G, Wennergren M, Vilbergsson G, Rosberg S. Longitudinal follow-up of growth in children born small for gestational age. Acta Paediatr. 1993; 82:438–443. PMID: 8518519.
Article
6. Karlberg J, Albertsson-Wikland K. Growth in full-term small-for-gestational-age infants: from birth to final height. Pediatr Res. 1995; 38:733–739. PMID: 8552442.
Article
7. Jaquet D, Collin D, Levy-Marchal C, Czernichow P. Adult height distribution in subjects born small for gestational age. Horm Res. 2004; 62:92–96. PMID: 15263821.
Article
8. Hokken-Koelega AC, De Ridder MA, Lemmen RJ, Den Hartog H, De Muinck Keizer-Schrama SM, Drop SL. Children born small for gestational age: do they catch up? Pediatr Res. 1995; 38:267–271. PMID: 7478827.
Article
9. Tuvemo T, Cnattingius S, Jonsson B. Prediction of male adult stature using anthropometric data at birth: a nationwide population-based study. Pediatr Res. 1999; 46:491–495. PMID: 10541308.
Article
10. Bayley N, Pinneau SR. Tables for predicting adult height from skeletal age: revised for use with the Greulich-Pyle hand standards. J Pediatr. 1952; 40:423–441. PMID: 14918032.
Article
11. Greulich WW, Pyle SI. Radiographic atlas of skeletal development of the hand and wrist. 2nd ed. Stanford: Stanford University Press;1959.
12. Lee JJ. Birth weight for gestational age patterns by sex, plurality, and parity in Korean population. Korean J Pediatr. 2007; 50:732–739.
Article
13. Korea Centers for Disease Control and Prevention (KCDC). Korean Pediatric Society, Committee for the Development of Growth Standard for Korean Children and Adolescents. 2007 Korean children and adolescents growth standard: commentary for the development of 2007 growth chart [Internet]. Cheongwon: KCDC, Division of Chronic Disease Surveillance;c2012. cited 2012 Aug 25. Available from: http://www.cdc.go.kr/CDC/info/CdcKrInfo0201.jsp?menuIds=HOME001-MNU0004-MNU0007-MNU0025&fid=28&q_type=&q_value=&cid=1235&pageNum=74.
14. Bhargava SK, Ramji S, Srivastava U, Sachdev HP, Kapani V, Datta V, et al. Growth and sexual maturation of low birth weight children: a 14 year follow up. Indian Pediatr. 1995; 32:963–970. PMID: 8935258.
15. Ghirri P, Bernardini M, Vuerich M, Cuttano AM, Coccoli L, Merusi I, et al. Adrenarche, pubertal development, age at menarche and final height of full-term, born small for gestational age (SGA) girls. Gynecol Endocrinol. 2001; 15:91–97. PMID: 11379014.
Article
16. Ibanez L, Jimenez R, de Zegher F. Early puberty-menarche after precocious pubarche: relation to prenatal growth. Pediatrics. 2006; 117:117–121. PMID: 16396868.
Article
17. Ibáñez L, Ferrer A, Marcos MV, Hierro FR, de Zegher F. Early puberty: rapid progression and reduced final height in girls with low birth weight. Pediatrics. 2000; 106:E72. PMID: 11061809.
18. Lazar L, Pollak U, Kalter-Leibovici O, Pertzelan A, Phillip M. Pubertal course of persistently short children born small for gestational age (SGA) compared with idiopathic short children born appropriate for gestational age (AGA). Eur J Endocrinol. 2003; 149:425–432. PMID: 14585089.
Article
19. Sloboda DM, Hart R, Doherty DA, Pennell CE, Hickey M. Age at menarche: Influences of prenatal and postnatal growth. J Clin Endocrinol Metab. 2007; 92:46–50. PMID: 17062767.
Article
20. Veening MA, van Weissenbruch MM, Roord JJ, de Delemarre-van Waal HA. Pubertal development in children born small for gestational age. J Pediatr Endocrinol Metab. 2004; 17:1497–1505. PMID: 15570986.
Article
21. Albertsson-Wikland K, Karlberg J. Natural growth in children born small for gestational age with and without catch-up growth. Acta Paediatr Suppl. 1994; 399:64–70. PMID: 7949620.
22. Jaquet D, Leger J, Chevenne D, Czernichow P, Levy-Marchal C. Intrauterine growth retardation predisposes to insulin resistance but not to hyperandrogenism in young women. J Clin Endocrinol Metab. 1999; 84:3945–3949. PMID: 10566632.
Article
23. Park MJ, Lee IS, Shin EK, Joung H, Cho SI. The timing of sexual maturation and secular trends of menarchial age in Korean adolescents. Korean J Pediatr. 2006; 49:610–616.
Article
24. Luo ZC, Albertsson-Wikland K, Karlberg J. Length and body mass index at birth and target height influences on patterns of postnatal growth in children born small for gestational age. Pediatrics. 1998; 102:E72. PMID: 9832600.
Article
25. Leger J, Limoni C, Collin D, Czernichow P. Prediction factors in the determination of final height in subjects born small for gestational age. Pediatr Res. 1998; 43:808–812. PMID: 9621992.
Article
26. Carel JC, Chatelain P, Rochiccioli P, Chaussain JL. Improvement in adult height after growth hormone treatment in adolescents with short stature born small for gestational age: results of a randomized controlled study. J Clin Endocrinol Metab. 2003; 88:1587–1593. PMID: 12679443.
Article
27. Van Pareren Y, Mulder P, Houdijk M, Jansen M, Reeser M, Hokken-Koelega A. Adult height after long-term, continuous growth hormone (GH) treatment in short children born small for gestational age: results of a randomized, double-blind, dose-response GH trial. J Clin Endocrinol Metab. 2003; 88:3584–3590. PMID: 12915640.
Article
28. Cho GJ, Park HT, Shin JH, Hur JY, Kim YT, Kim SH, et al. Age at menarche in a Korean population: secular trends and influencing factors. Eur J Pediatr. 2010; 169:89–94. PMID: 19504269.
Article
29. Rigon F, Bianchin L, Bernasconi S, Bona G, Bozzola M, Buzi F, et al. Update on age at menarche in Italy: toward the leveling off of the secular trend. J Adolesc Health. 2010; 46:238–244. PMID: 20159500.
Article
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