J Korean Assoc Maxillofac Plast Reconstr Surg.
2000 Mar;22(2):142-154.
Effect of Methylprednisolone on the Healing Process after Medpor Implantation in Rats
- Affiliations
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- 1Department of Oral and Maxillofacial Surgery, Oral Biology Research Institute College of Dentistry, Chosun University.
- 2Department of Anesthesiology, College of Dentistry, Chonnam University.
Abstract
- The purpose of this study is to evaluate the difference in healing of Medpor implants of two different thickness (1.5mm and 4.5mm) and the effects of methylprednisolone on the healing process. Light microscopic and scanning electron microscopic examinations, and hardness measurement were made in 100 rats 2, 4, or 8 weeks postoperatively. The 1.5mm thin implants were taken better than the 4.5mm thick implants. The inflammatory responses were reduced after application of methylprednisolone with arrangement and amount of bone matrix deposited being more irregular and reduced in bulk than in the control group. To hasten postoperative healing after Medpor implantation, the thinner material should be used and steroid injection should be avoided.
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