J Korean Soc Radiol.  2013 Oct;69(4):265-268. 10.3348/jksr.2013.69.4.265.

Epithelial-Myoepithelial Carcinoma in Nasal Cavity with Bony Destruction: A Case Report

• Chung HJ
• Lee BH
• Hwang YJ
• Kim SY

• KMID: 2041944
• DOI: http://doi.org/10.3348/jksr.2013.69.4.265

Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare tumor that commonly involves the salivary glands. EMC arising from the nasal cavity is one of the most unusual cases. We describe a case of a 48-year-old patient who is presented with bilateral nasal obstruction for several months. Multidetector computed tomography reveals expansile, well-defined, heterogeneous enhancing soft tissue masses filling the nasal cavity with bony destruction of hard palate and maxillary alveolar ridge. The carcinoma was histologically characterized by a mixture of trabecular structure with myoepithelial cells and ductal cells, which are confirmed by electron microscopy and immunohistochemistry.

MeSH Terms

Alveolar Process
Humans
Immunohistochemistry
Microscopy, Electron
Middle Aged
Multidetector Computed Tomography
Nasal Cavity
Nasal Obstruction
Palate, Hard
Salivary Glands

Figure

• 

  Fig. 1 A 48-year-old woman with epithelial-myoepithelial tumor in nasal cavity. A. An expansile well-marginated soft tissue mass, filling the nasal cavity, shows heterogenous nature on non-enhancing axial CT scan (arrows). B. On enhanced axial CT scan shows multiloculated low attenuation lesions (thin arrows) and septum like enhancing portion in mass (thick arrow). C. Mass extends into nasopharyngeal space posteriorly (thin arrow) and there was also bony destruction of hard palate and maxillary alveolar ridge due to tumor invasion on sagittal CT sacn (thick arrows). D. Each tubules are lined by two layers of cells, inner eosinophilic epithelial cells and outer myoepithelial cells (hematoxylin-eosin, × 400). E. Immunohistochemical analysis shows that the expression of p63 (original magnification, × 400). F. Immunohistochemical analysis shows that the expression of Ki67 (original magnification, × 400).

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