Korean J Dermatol.  1970 Jul;8(2):17-21.

Studies on Side Effects of Various Soaps, Cosmetics and Topical Medicaments: I. Path Tests with Some Materials

• Lee YS

Abstract

The routine closed patch tests were performe0 with 41 kinds of domestic soaps, detergents, cosm etics and topical medicaments (incIuding a adhesive plaster) on the intact skin of the back of 100 adult males without any dermatoses, to evaluate their side effects on the skin. 1, None of the materials showed no positive reaction, 2, The over all positive reactions were observed in 21.l% of my subjects, including a 1+reacti ons in,l6,4% and a 2+or 3, In 4.7% 3, In 12 kinds of soaps, Positive reaction wer observed in 19-33% positive of my subjects (average Z7.8%) 4, In 4 kinds of detergents, positive reations were observed in 6-19% of my subjects (average 9,7%), in which the highest reaction rate revealed was IVonderful of Dongsan fats and oils co.. 5. The positive reactiors in 3 kinds of toothpastes were observed in 37-61% of my subjects (average 50.7%). 6. The positive reactions to the adhesive plaster were observed in 25% of my subjects. Arnong 17 kinds of topial medicaments, positive reaction rates above 10 shown were Aroos oirtment of Sarn-A phaxmaceutical co. (49%), PM spirit of Kyungnam pharmaceutical co. (16%), Periio ointment of Namgang pharmaceutical co. (13%), Badional-Gel of Hanil pharm-aceutcal co. (10%) and Antiphlamine of Yuhan corporation (10%). 8. In 4 kinds of cosmetic creams, all showed higher positive reaction rates, i.e, "Masan Joongang cream of Yeinvonlang No I, 41%;No.2, 35%;N0.3, 32% and E.mong cream" of Daido phanna-ceutical co,44%.

MeSH Terms

Adhesives
Adult
Detergents
Fats
Gyeongsangnam-do
Humans
Male
Oils
Patch Tests
Skin
Skin Diseases
Soaps*
Toothpastes
Adhesives
Detergents
Fats
Oils
Soaps
Toothpastes