Korean J Dermatol.  2002 Dec;40(12):1493-1497.

Efficacy of Oral Fluconazole 300mg Once Weekly for Two Weeks in Treatment of Pityriasis Versicolor

• Lim OH
• Lee JB
• Kim SJ
• Won YH
• Lee SC

Abstract

PURPOSE: This study was designed to assess the efficacy, tolerability and safety of oral fluconazole in the treatment of pityriasis versicolor(PV).
METHODS
Fifty-nine patients, 48 males and 11 females aged 12-57(mean 30 years) were enrolled in this study. Oral fluconazole in 300mg single dosage once weekly for 2 weeks was administered. Clinical and mycological evaluation by global assessment, Wood's lamp examination, and KOH mount was performed. Evaluation was done before and after treatment, at week 1, 2, 3, 4 and 6.
RESULTS
Forty-two patients(71.2%) showed clinical and mycological response at week 6. Tolerability of the drug was acceptable while two patients experienced mild dizziness during the therapy. Otherwise, there were no significant side effects to be attentioned.
CONCLUSION
Oral fluconazole could be considered as an effective and safe alternative in the treatment of pityriasis versicolor.

Keyword

Fluconazole; Pityriasis versicolor

MeSH Terms

Dizziness
Female
Fluconazole*
Humans
Male
Pityriasis*
Tinea Versicolor*
Fluconazole