Korean J Urol.  1993 Feb;34(1):78-82.

The prostate specific antigen in detection of the prostate cancer

• Lee HC
• Hong CD
• Park JS
• Kim KB

Abstract

We measured the concentration of serum PSA and prostatic acid phosphatase for studying the usefulness of PSA in 145 cases with BPH and 24 cases with prostate cancer. PSA was more sensitive and same specific as PAP in diagnosis of prostate cancer(n < or = 20 ng/ml). The diagnostic accuracy and positive predictive rate or PSA were higher than PAP, positive predictive rate war highest in PSA(n < or = 10 ng/ml) with abnormal digital rectal examination. PSA was a simple and useful method for detection of prostate cancer. But, by strict statistical criteria alone, PSA by itself didn`t qualify as an effective screening tool. By combination with digital rectal examination and transrectal ultrasonography, it may be useful in early detection of prostate cancer.

Keyword

Prostate specific antigen; Prostate cancer

MeSH Terms

Acid Phosphatase
Diagnosis
Digital Rectal Examination
Mass Screening
Prostate*
Prostate-Specific Antigen*
Prostatic Neoplasms*
Ultrasonography
Acid Phosphatase
Prostate-Specific Antigen