Korean J Cerebrovasc Surg.  2006 Dec;8(4):287-289.

Aneurysmal Subarachnoid Hemorrhage Associated with Achondroplasia: Case Report

Affiliations
  • 1Department of Neurosurgery, Hanyang University Medical Center, Seoul, Korea. sklee737@hanmail.net

Abstract

Patients with achondroplasia manifest various neurologic symptoms including megaencephaly, hydrocephalus, and progressive myelopathy or radiculopathy secondary to spinal stenosis. However, only anecdotal postmortem reports proved ruptured aneurysm or vascular malformation as a source of intracranial hemorrhage. We herein report a case of a 26-year-old woman with achondroplasia who underwent uneventful surgical treatment for the aneurysmal subarachnoid hemorrhage. In this literature, we review the pathophysiologic mechanism and emphasize the necessity of considering the possibility of sudden mental deterioration in achondroplastic patient.

Keyword

Achondroplasia; Subarachnoid hemorrhage; Intracranial aneurysm

MeSH Terms

Achondroplasia*
Adult
Aneurysm*
Aneurysm, Ruptured
Female
Humans
Hydrocephalus
Intracranial Aneurysm
Intracranial Hemorrhages
Neurologic Manifestations
Radiculopathy
Spinal Cord Diseases
Spinal Stenosis
Subarachnoid Hemorrhage*
Vascular Malformations
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