Korean J Occup Environ Med.  2003 Sep;15(3):252-260.

Investigation of Occupational Dermatological Problem with Additives in Polypropylene Manufacturing Process

Affiliations
  • 1Department of Occupational and Environmental Medicine, School of Public Health, Seoul National University, Korea. deadbank@hanmail.net
  • 2Department of Dermatology, Seoul National University, College of Medicine, Korea.

Abstract


OBJECTIVES
To investigate the causative agents for the dermatological problems associated with the polypropylene manufacturing process.
METHODS
The study subjects consisted of 44 male workers involved in the polypropylene manufacturing process. Twenty-seven of them had been exposed to additives, and the remaining 17 had not. Among the 27 exposed, 10 had been exposed previously, and 17 are currently being exposed through their duties. Patch test were performed with three different concentrations, 0.1%, 1% and 10% of 10 different additives that was diluted with Vaseline.
RESULTS
18 subjects (41%) had positive reactions to the patch tests. Exposed group had a higher reaction rate (51.9%) than the control group (23.5%). When the positive reactions were further classified, 7, 6 and 5 were compatible with probably irritant, probably allergic, and multiple hypersensitivity reactions respectively. The most frequent reactions were from Ultranox-626 followed by Millad 3988, Armoslip-E and Songstab Sc-100.
CONCLUSIONS
When considering the significantly higher probability of an allergic reaction rate among the currently exposed group compared to non- or previously-exposed groups, the nature of dermatological problems in a polypropylene plant is probably allergic. Ultranox-626, Millad3988, Armoslip-E and Songstab Sc-100 were the main causatives agents found in the process.

Keyword

Patch Tests; Polypropylenes; Irritants; Hypersensitivity

MeSH Terms

Humans
Hypersensitivity
Irritants
Male
Patch Tests
Petrolatum
Plants
Polypropylenes*
Irritants
Petrolatum
Polypropylenes
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