Korean J Occup Environ Med.  2003 Mar;15(1):111-117.

Exfoliative Dermatitis and Toxic Hepatitis Associated with Occupational Exposure to Trichloroethylene

Affiliations
  • 1Department of Occupational and Environmental Medicine, Chonnam National University Hospital, Korea. ajdmoon@chollian.net
  • 2Department of Dermatology, Chonnam National University Hospital, Korea.
  • 3Department of Internal Medicine, Chonnam National University Hospital, Korea.

Abstract

A 28-year-old male began working as a degreaser. The solvent used in the degreasing operation was trichloroethylene. Over the next month the man experienced fever, chills, and an erythematous skin rash and itching. At that time he had a marked elevation in his liver enzyme, with cholestasis. Over the next few days the rash persisted then peeled. There was an elevation of Ig E, and a positive patch test reaction to trichloroethylene. His dermatitis and hepatitis were considered to be mediated by a hypersensitivity mechanism.

Keyword

Trichloroethylene; Hepatitis; Exfoliative dermatitis

MeSH Terms

Adult
Chills
Cholestasis
Dermatitis
Dermatitis, Exfoliative*
Drug-Induced Liver Injury*
Exanthema
Fever
Hepatitis
Humans
Hypersensitivity
Liver
Male
Occupational Exposure*
Patch Tests
Pruritus
Trichloroethylene*
Trichloroethylene
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