Korean J Occup Environ Med.
2003 Mar;15(1):111-117.
Exfoliative Dermatitis and Toxic Hepatitis Associated with Occupational Exposure to Trichloroethylene
- Affiliations
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- 1Department of Occupational and Environmental Medicine, Chonnam National University Hospital, Korea. ajdmoon@chollian.net
- 2Department of Dermatology, Chonnam National University Hospital, Korea.
- 3Department of Internal Medicine, Chonnam National University Hospital, Korea.
Abstract
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A 28-year-old male began working as a degreaser. The solvent used in the degreasing operation was trichloroethylene. Over the next month the man experienced fever, chills, and an erythematous skin rash and itching. At that time he had a marked elevation in his liver enzyme, with cholestasis. Over the next few days the rash persisted then peeled. There was an elevation of Ig E, and a positive patch test reaction to trichloroethylene. His dermatitis and hepatitis were considered to be mediated by a hypersensitivity mechanism.